Androgen
Drug Details
- Description
- Androgens are a group of hormones, including testosterone, that regulate male traits and reproductive activity. They promote the development of male secondary sexual characteristics, such as increased muscle and bone mass, and the growth of body hair.
- Alternative Names
- Androgen.
- Key Genes
- Androgen action involves key genes like AR (androgen receptor), SRD5A2 (steroid-5-alpha-reductase, alpha polypeptide 2), CYP17A1 (cytochrome P450 family 17 subfamily A member 1), HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3), and SHBG (sex hormone-binding globulin).
- Drug Use
- Androgens are used therapeutically to treat conditions like male hypogonadism, delayed puberty in boys, certain types of breast cancer in women, and as part of hormone therapy for transgender men. They enhance muscle mass and are also used off-label by athletes for performance enhancement, though this is illegal and banned in sports.
- Genetic Factors Influencing Response
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