Antidepressant
Drug Details
- Description
- Antidepressants are medications used to treat various forms of depression by altering chemicals (neurotransmitters) in the brain to help improve mood and emotional state. Common types include SSRIs, SNRIs, MAOIs, and tricyclic antidepressants.
- Alternative Names
-
Antidepressant:
- Generic names: fluoxetine, sertraline, escitalopram, venlafaxine, duloxetine
- Brand names: Prozac, Zoloft, Lexapro, Effexor, Cymbalta - Key Genes
-
Key genes involved in the response to antidepressants include:
1. **SLC6A4** - encodes the serotonin transporter.
2. **HTR2A** - encodes the 5-HT2A receptor.
3. **BDNF** - brain-derived neurotrophic factor.
4. **COMT** - catechol-O-methyltransferase.
5. **FKBP5** - involved in glucocorticoid receptor regulation.
6. **CYP2D6** - involved in the metabolism of many antidepressants.
7. **CYP2C19** - another enzyme important for the metabolism of certain antidepressants. - Drug Use
- Antidepressants are used to treat major depressive disorder, anxiety disorders, chronic pain conditions, and sometimes for insomnia.
- Genetic Factors Influencing Response
-
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Purchase Membership to Access Your Individual Drug Response Report