Carbamazepine
Drug Details
- Description
- Carbamazepine is an anticonvulsant and mood-stabilizing drug primarily used to treat epilepsy, bipolar disorder, and neuropathic pain. It works by reducing abnormal electrical activity in the brain.
- Alternative Names
- Carbamazepine
- Key Genes
- Key genes involved in the pharmacogenetics of carbamazepine include HLA-B, specifically the HLA-B*15:02 allele, and CYP3A4, CYP3A5, as these variants affect drug metabolism and risk of adverse reactions.
- Drug Use
- Carbamazepine is primarily used to treat epilepsy, specifically partial seizures and generalized tonic-clonic seizures. It is also prescribed for trigeminal neuralgia and bipolar disorder.
- Genetic Factors Influencing Response
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