Codeine
Drug Details
- Description
- Codeine is an opioid analgesic used to treat mild to moderately severe pain and to suppress cough. It can be habit-forming and is often combined with other medications like acetaminophen. Codeine is metabolized in the liver to morphine, which is primarily responsible for its pain-relieving effects.
- Alternative Names
- Codeine.
- Key Genes
- Key genes involved in the metabolism of Codeine include CYP2D6, CYP3A4, and UGT2B7. CYP2D6 metabolizes Codeine to morphine, which is its active form. Variations in CYP2D6 can significantly affect drug efficacy and safety.
- Drug Use
- Codeine is an opioid used to treat mild to moderate pain and to reduce coughing. It is available by prescription and often combined with other medications like acetaminophen. Misuse can lead to addiction, respiratory issues, and overdose.
- Genetic Factors Influencing Response
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