Corticosteroids
Drug Details
- Description
- Corticosteroids are anti-inflammatory drugs used to treat conditions like asthma, rheumatoid arthritis, and lupus. They mimic cortisol, a hormone produced by the adrenal glands, and help reduce inflammation and suppress the immune system.
- Alternative Names
- Prednisone, Hydrocortisone, Dexamethasone, Methylprednisolone, Betamethasone.
- Key Genes
- Key genes involved with corticosteroid response include NR3C1 (glucocorticoid receptor), HSD11B1 (11β-hydroxysteroid dehydrogenase type 1), and CYP3A4 (cytochrome P450 3A4 enzyme).
- Drug Use
- Corticosteroids are used to reduce inflammation and suppress the immune system. They treat conditions like asthma, arthritis, lupus, inflammatory bowel disease, and allergies. They are also used for adrenal insufficiency and to reduce swelling from injuries.
- Genetic Factors Influencing Response
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