Debrisoquine
Drug Details
- Description
- Debrisoquine is an antihypertensive agent and an adrenergic neuron-blocking drug. It works by inhibiting the release of norepinephrine from sympathetic nerve terminals, leading to vasodilation and reduced blood pressure. It is primarily used in research to study polymorphisms in drug metabolism, particularly cytochrome P450 2D6.
- Alternative Names
- Debrisoquine
- Key Genes
- The key gene for Debrisoquine metabolism is CYP2D6.
- Drug Use
- Debrisoquine is primarily used as an antihypertensive agent to treat high blood pressure. It is also used in pharmacogenetic research to study individual variations in drug metabolism.
- Genetic Factors Influencing Response
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