Ezetimibe
Drug Details
- Description
- Ezetimibe is a cholesterol absorption inhibitor used to reduce elevated cholesterol levels by preventing the absorption of cholesterol from the small intestine.
- Alternative Names
- Ezetimibe.
- Key Genes
- Key genes associated with the action of Ezetimibe include NPC1L1 (encodes Niemann-Pick C1-Like 1 protein, the target of Ezetimibe) and ABCG5/ABCG8 (genes involved in sterol transport and cholesterol homeostasis).
- Drug Use
- Ezetimibe is used to lower cholesterol levels in the blood by reducing the amount of cholesterol absorbed by the intestines. It is often prescribed for individuals with high cholesterol or those who need additional lowering of cholesterol beyond what is achieved with statins or other medications.
- Genetic Factors Influencing Response
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