Fluorouracil
Drug Details
- Description
- Fluorouracil is an antimetabolite chemotherapy drug used to treat various cancers, including colorectal, breast, stomach, and pancreatic cancers. It inhibits thymidylate synthase, disrupting DNA synthesis and cell division.
- Alternative Names
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Common name: Fluorouracil
Synonyms: 5-FU, Adrucil, Carac, Efudex, Fluoroplex - Key Genes
- Key genes involved with Fluorouracil include DPYD, TYMS, and MTHFR.
- Drug Use
- Fluorouracil is used to treat certain types of cancer, including cancers of the colon, rectum, breast, stomach, and pancreas. It can also be used topically to treat actinic keratoses and superficial basal cell carcinoma.
- Genetic Factors Influencing Response
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