Flurbiprofen
Drug Details
- Description
- Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce inflammation and pain in conditions like arthritis. It works by inhibiting cyclooxygenase (COX) enzymes, which play a role in the synthesis of prostaglandins involved in inflammation, pain, and fever. Flurbiprofen is available in oral and topical forms.
- Alternative Names
- Flurbiprofen is commonly marketed under the brand name Ansaid.
- Key Genes
- Key genes related to flurbiprofen metabolism and response include CYP2C9, which is involved in its metabolism, and PTGS1 and PTGS2, which encode cyclooxygenase enzymes (COX-1 and COX-2) targeted by flurbiprofen. Variants in CYP2C9 can affect the drug's clearance and efficacy.
- Drug Use
- Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation associated with conditions like arthritis and to reduce minor aches, pains, and fever. It is also used in an ophthalmic form to prevent eye inflammation during and after surgery.
- Genetic Factors Influencing Response
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