Gemcitabine
Drug Details
- Description
- Gemcitabine is a nucleoside analog used as chemotherapy. It inhibits DNA synthesis, primarily used to treat various cancers, including non-small cell lung cancer, pancreatic cancer, bladder cancer, and breast cancer.
- Alternative Names
- Gemcitabine, marketed as Gemzar.
- Key Genes
- The key genes associated with Gemcitabine include CDA (Cytidine Deaminase), DCK (Deoxycytidine Kinase), RRM1 (Ribonucleotide Reductase Catalytic Subunit M1), and RRM2 (Ribonucleotide Reductase Regulatory Subunit M2).
- Drug Use
- Gemcitabine is used to treat various cancers, including pancreatic cancer, non-small cell lung cancer, bladder cancer, and breast cancer.
- Genetic Factors Influencing Response
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