Gentamicin
Drug Details
- Description
- Gentamicin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, effective against aerobic Gram-negative bacteria. It is commonly used to treat severe infections like sepsis, respiratory tract infections, and urinary tract infections.
- Alternative Names
- Gentamicin is an aminoglycoside antibiotic.
- Key Genes
- Key genes associated with gentamicin include MT-RNR1 for mitochondrial toxicity and GJB2 for congenital hearing loss. These genes can influence susceptibility to ototoxicity and nephrotoxicity.
- Drug Use
- Gentamicin is an antibiotic used to treat severe bacterial infections, especially those caused by Gram-negative bacteria. Typically, it's administered intravenously or intramuscularly.
- Genetic Factors Influencing Response
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