Ivacaftor
Drug Details
- Description
- Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used to treat cystic fibrosis in patients with specific CFTR gene mutations. It enhances the function of the defective CFTR protein, improving chloride transport and hydration of airway surfaces.
- Alternative Names
- Ivacaftor is also known as VX-770.
- Key Genes
- Ivacaftor targets the CFTR (cystic fibrosis transmembrane conductance regulator) gene.
- Drug Use
- Ivacaftor is used to treat cystic fibrosis in patients with specific mutations in the CFTR gene. It improves lung function and reduces symptoms by aiding the function of the defective protein produced by the CFTR gene.
- Genetic Factors Influencing Response
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