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Lesinurad

Drug Details

Description
Lesinurad is a selective uric acid reabsorption inhibitor (SURI) used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout. It works by inhibiting the function of the URAT1 transporter, reducing serum uric acid levels.
Alternative Names
Lesinurad.
Key Genes
The key gene associated with Lesinurad is SLC22A12, which encodes the URAT1 protein involved in uric acid reabsorption in the kidneys.
Drug Use
Lesinurad is used to treat hyperuricemia associated with gout. It works by inhibiting the function of proteins involved in uric acid reabsorption in the kidneys, thereby increasing uric acid excretion.
Genetic Factors Influencing Response

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