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Letrozole

Drug Details

Description
Letrozole is an oral nonsteroidal aromatase inhibitor used primarily for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by decreasing estrogen levels in the body, which can slow or stop the growth of certain types of breast tumors that require estrogen to grow.
Alternative Names
Letrozole is commonly known by its brand name, Femara.
Key Genes
Key genes associated with Letrozole include CYP19A1, ESR1, and ESR2.
Drug Use
Letrozole is used to treat hormone receptor-positive breast cancer in postmenopausal women. It can be used as adjuvant treatment, extended adjuvant treatment, or for metastatic breast cancer. It works by decreasing estrogen levels.
Genetic Factors Influencing Response

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