Mitogen-activated
Drug Details
- Description
- Mitogen-activated protein kinases (MAPKs) are a family of serine/threonine protein kinases involved in cellular responses to a variety of stimuli, including mitogens, stress, and proinflammatory cytokines. They play crucial roles in cell proliferation, differentiation, and survival.
- Alternative Names
- MKK (Mitogen-Activated Protein Kinase Kinase).
- Key Genes
- Key genes involved in Mitogen-Activated Protein Kinase (MAPK) pathways include MAPK1 (ERK2), MAPK3 (ERK1), MAPK8 (JNK1), MAPK9 (JNK2), MAPK14 (p38 alpha), and MAP2K1 (MEK1).
- Drug Use
- Mitogen-activated drugs are not a specific category of drugs. However, mitogen-activated protein kinases (MAPKs) are often targeted in drug development for conditions involving cell growth, inflammation, and stress responses. Drugs targeting MAPKs may be used in cancer therapy and inflammatory diseases.
- Genetic Factors Influencing Response
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