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Rosuvastatin

Drug Details

Description
Rosuvastatin is an HMG-CoA reductase inhibitor, also known as a statin, used to lower cholesterol and triglycerides in the blood. It helps reduce the risk of cardiovascular events such as heart attack and stroke.
Alternative Names
Rosuvastatin calcium
Key Genes
- **SLCO1B1:** Gene encoding OATP1B1, important for hepatic uptake.
- **ABCB1:** Gene encoding P-glycoprotein, affects drug efflux.
- **CYP2C9:** Enzyme involved in metabolism.
- **CETP:** Gene associated with lipid levels response.
- **HMGCR:** Target gene encoding HMG-CoA reductase.
Drug Use
Rosuvastatin is used to lower cholesterol and triglyceride levels in the blood, reducing the risk of cardiovascular disease, heart attacks, and strokes. It belongs to the statin class of drugs.
Genetic Factors Influencing Response

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