Sertraline
Drug Details
- Description
- Sertraline is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, anxiety disorders, panic attacks, and obsessive-compulsive disorder. It increases serotonin levels in the brain to help improve mood and reduce symptoms.
- Alternative Names
- Sertraline
- Key Genes
- The key genes associated with sertraline metabolism and response include CYP2C19, CYP2D6, and SLC6A4. CYP2C19 and CYP2D6 are involved in the drug's metabolism, while SLC6A4 encodes the serotonin transporter, which is the target of sertraline. Variations in these genes can affect drug efficacy and risk of side effects.
- Drug Use
- Sertraline is primarily used to treat major depressive disorder, anxiety disorders, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).
- Genetic Factors Influencing Response
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