Tamoxifen
Drug Details
- Description
- Tamoxifen is a selective estrogen receptor modulator (SERM) commonly used to treat and prevent breast cancer. By binding to estrogen receptors, it inhibits estrogen's effects, which can slow or stop the growth of hormone receptor-positive breast cancer cells.
- Alternative Names
- Tamoxifen.
- Key Genes
- Key genes for Tamoxifen include CYP2D6 and CYP3A4. These genes influence the drug's metabolism and effectiveness. Variations in CYP2D6 can affect the conversion of Tamoxifen to its active metabolites.
- Drug Use
- Tamoxifen is primarily used to treat and prevent breast cancer by interfering with the effects of estrogen in the breast tissue. It is also used to reduce the risk in high-risk patients and treat other conditions as determined by a doctor.
- Genetic Factors Influencing Response
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