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Tegafur

Drug Details

Description
Tegafur is a prodrug of the anticancer agent 5-fluorouracil (5-FU) used in chemotherapy. It is often combined with other agents to enhance its efficacy and reduce side effects.
Alternative Names
Tegafur.
Key Genes
Key genes associated with Tegafur: DPYD, TYMS, MTHFR, and CYP2A6.
Drug Use
Tegafur is used primarily in the treatment of several types of cancers, including colorectal and gastric cancer. It is an antineoplastic agent that works by inhibiting DNA synthesis in cancer cells. Often, it is used in combination with other drugs like uracil and gimeracil.
Genetic Factors Influencing Response

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