Tretinoin
Drug Details
- Description
- Tretinoin is a topical retinoid used to treat acne, fine wrinkles, and mottled skin discoloration. It promotes cell turnover and prevents the formation of new acne lesions.
- Alternative Names
- Tretinoin is also known as all-trans retinoic acid (ATRA).
- Key Genes
- Tretinoin, or all-trans-retinoic acid (ATRA), influences gene expression by binding to retinoic acid receptors (RARs). Key genes affected include **RAR**, **RXR**, **CYP26A1**, and **BMP2**.
- Drug Use
- Tretinoin is used primarily for the treatment of acne, reducing the appearance of fine wrinkles, and improving skin texture. It is also employed in the treatment of acute promyelocytic leukemia.
- Genetic Factors Influencing Response
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