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Voriconazole

Drug Details

Description
Voriconazole is a triazole antifungal medication used to treat serious fungal infections, including invasive aspergillosis and candidemia. It works by inhibiting the enzyme cytochrome P450 14α-demethylase, disrupting fungal cell membrane synthesis.
Alternative Names
Voriconazole.
Key Genes
Key genes associated with Voriconazole include CYP2C19, CYP3A4, CYP2C9, and POR. Variants in these genes can affect drug metabolism and response.
Drug Use
Voriconazole is an antifungal medication used primarily to treat serious fungal infections such as invasive aspergillosis, candidemia, esophageal candidiasis, and infections caused by Scedosporium and Fusarium species.
Genetic Factors Influencing Response

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