Warfarin
Drug Details
- Description
- Warfarin is an anticoagulant that inhibits vitamin K-dependent clotting factors, reducing blood clot formation. It's used to prevent and treat thromboembolic disorders, such as deep vein thrombosis and pulmonary embolism.
- Alternative Names
- Warfarin is also known as Coumadin.
- Key Genes
- Key genes affecting Warfarin response include CYP2C9 and VKORC1. CYP2C9 variants influence Warfarin metabolism, while VKORC1 variants affect Warfarin sensitivity.
- Drug Use
- Warfarin is used to prevent and treat blood clots, including deep vein thrombosis (DVT), pulmonary embolism (PE), and to reduce the risk of stroke and heart attack in patients with atrial fibrillation, artificial heart valves, or after certain surgeries.
- Genetic Factors Influencing Response
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